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작성자 Florrie
댓글 0건 조회 21회 작성일 23-07-06 09:00

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Aplastic Anemia and MDS International Foundation

The Aplastic Anemia and MDS International Foundation is dedicated to helping families and patients with Aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria. The Foundation also conducts research into bone marrow failure disease and other related conditions.

CN railroad employees are frequently exposed to diesel exhaust when working around locomotives or canadian national railway Scleroderma other railway equipment. This exposure can lead to occupational lung disease and blood disorders.

Causes

Aplastic anemia is caused by the damage to blood stem cells, which are responsible for producing blood-forming cells (red blood cells, white blood cells and platelets). The bone marrow is unable to produce enough healthy cells. This condition can be very dangerous and even life-threatening.

Radiation and chemotherapy treatments used to treat cancer can cause aplastic anemia by damaging the bone marrow stem cells. This type of aplastic anemia generally improves after these treatments have been completed.

This condition is usually caused by exposure to diesel exhaust. Diesel exhaust can cause blood disorders, respiratory problems and other health issues for railroad workers.

Medications, such as colony-stimulating factors (sargramostim and leucovorin) or granulocyte colony stimulating factor which stimulates your bone marrow, which can produce more blood cells and prevent anemia. These drugs are commonly used in conjunction with immune-suppressing medication, like cyclosporine, Neoral, Sandimmune, and anti-thymocyte-globulin. For those suffering from autoimmune-related aplastic anemia, avoiding insecticides, organic solvents, herbicides paint removers and other harmful chemicals may decrease your risk of this condition. Antibiotics can reduce your risk. If you develop an infection, your doctor may prescribe high doses of corticosteroids like methylprednisolone, SoluMedrol or Medrol.

Diagnosis

A doctor typically diagnoses this condition by looking over your medical history, family history, and performing an exam. Test results can also be used to confirm the diagnosis. If he suspects you are suffering from this condition, he might refer you to a specialist called a hematologist (hem-A-tox). He will try to determine how severe the condition is and also what's causing it.

A hematologist performs a series of tests to check your bone and blood vessels for abnormalities. A complete blood count (CBC) which is a measure of the red and white blood cells are one of these tests. The test also measures the levels of hemoglobin and hemoglobin levels and hematocrit. These iron-rich proteins carry oxygen to cells in your body. Anemia is indicated by having a low hematocrit.

The CBC can also indicate whether your immune system functions normally or not. It can also detect enlarged lymph nodes which are a sign of specific types of cancer. A hematologist can also look at your liver and spleen for indications of liver disease or infection.

A hematologist can also order a bone-marrow biopsy or aspiration in addition to these tests. This test involves removing bone marrow liquid and examining it under a magnifying microscope for any blood cells that are not functioning properly. A hematologist might also recommend an operation to transplant bone marrow in the event that your condition can't be treated with medication.

Treatment

Diesel exhaust has been linked to aplastic anemia, and train drivers and other railroad workers are at risk. Aplastic anemia can be caused by benzene which is a chemical found in petroleum-based substances like solvents, paint thinners, degreasers, lubricants and other cleaners. It's also used in inks, glues as well as inks, rubbers and inks. Workers who are exposed to benzene at work, like mechanics, refinery workers, oilfield workers, boilermakers, pressmen, tanker truck and drill drivers are more likely to develop the disease.

The majority of aplastic anemia is due to your immune system mistakenly attacking your bone marrow and it can be treated with drugs that suppress your immune system. These medicines, also known as immunosuppressants include cyclosporine (Gengraf, Neoral, Sandimmune) and anti-thymocyte globulin. Transfusions of blood, as well as certain drugs that increase bone marrow could also help relieve symptoms.

A cure for PNH as well as other bone marrow dysfunction disorders is being investigated as well. The Aplastic Anemia and Myelodysplastic Syndrome International Foundation and the canadian national railway pulmonary fibrosis Organization for Rare Disorders are sponsoring the biggest-ever study on hemoglobinuria with paroxysmal nocturnal manifestations. Other studies will concentrate on aplastic anemia, myelodysplastic syndrome and leukemia. They will be conducted at a variety of medical centers across Canada, the United States and Europe.

The following is a list of preventions.

canadian national railway Scleroderma canadian national railway pancreatic cancer canadian national railway throat cancer, founded on 6 June 1919, is the only transcontinental railway network in North America. A Crown corporation at the time of its creation it grew to encompass a variety of businesses, including marine operations, hotels and telecommunications, but its primary business is canadian national railway mds transportation. Under the dynamic presidency of Donald Gordon, CN modernized its infrastructure and streamlined its 80 subsidiary companies down to 30 and then converted to diesel locomotives and electronic signalling. CN Exploration was formed to expand CN's mineral rights. CN Real Estate was formed to renovate downtown properties owned by the company in various cities, including the CN Tower.

Construction workers who construct and maintain railway tracks are often exposed to diesel exhaust. Cabs that are not ventilated properly allow harmful fumes to be absorbed back onto skin and clothing, creating conditions that can cause occupational cancers, blood disorders and pulmonary issues. Potential donors are advised to participate in local stem cell registry drives like the one taking place this week at St. Matthews High School 6550 Bilberry Drive. Those who match will be contacted for further testing.

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