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Multiple Myeloma and csx transportation laryngeal cancer Transportation
Peter worked for the Long Island Railroad Company for 29 years. During that time Peter was exposed to several hazardous chemicals. These substances and chemicals included creosote and diesel fumes.
Multiple myeloma is a cancer that affects plasma cells, which are responsible for producing antibodies to fight infections and diseases. These cancerous cells multiply within bones, forming cancerous tumors known as plasmacytomas.
Symptoms
The cancer affects plasma cells, which create antibodies that help the body fight germs and infections. The symptoms of multiple myeloma are bone pain in the back and ribs, brittle bones which break easily as well as fatigue, weakness loss of appetite, fatigue and kidney issues.
Often, myeloma does not cause symptoms until it is in its early stages. A doctor might not be aware of it until an annual blood or urine test for another condition has higher levels of protein than normal. This is known as myeloma smoldering. Myeloma can cause damage to organs, such as the kidneys, lungs, or nervous system in its later stages. This can result in vision and balance problems.
Your outlook is affected by the stage of your myeloma and other health conditions and also the age at which you were diagnosed. Your prognosis is also affected by how many plasma cells are producing tumors and creating complications as well as genetic factors that influence your risk of developing myeloma.
People who have a chromosomal anomaly known as deletion 17p or duplication 18q have a worse chance of surviving than people who don't have these disorders. If your kidneys do not perform as well, you'll have a less favorable prospect of survival. The amount of creatinine that you find in your blood is an excellent indicator of how your kidneys are working.
Diagnosis
Multiple myeloma is diagnosed after a person's blood or urine is tested for another illness and csx transportation pancreatic cancer more than the normal amount of protein is detected. Myeloma symptoms include bone pain, weakness of bones (including the back and ribs) and kidney issues, a fever without a known cause, bruising and difficult breathing.
The disease is more prevalent for people over the age of 60, and it is most often seen in males over 60. People with a first-degree relative who suffers from myeloma have 2 to 3 times greater risk of being diagnosed than other people. This includes siblings, parents, and children.
There are a variety of risk factors for myeloma. This includes a previous diagnosis of a single plasmacytoma of the bone or an extramedullary blood clot in soft tissue (such as the lung or throat). Myeloma is more frequent in people who have been exposed either to radiation or chemicals like asbestos, pesticides and benzene. Myeloma is also more prevalent for those who have a high monoclonal-gammopathy of unknown significance (MGUS).
The expert witnesses for the plaintiffs included two toxicologists and one epidemiologist. Toxicology refers to the science which studies the ways in which a chemical could be harmful and csx transportation pancreatic cancer the way exposure can cause a disease. Epidemiology studies the causes and effects, such as those caused by myeloma. This is accomplished by examining medical records and statistics.
Treatment
The treatment of myeloma focused on radiation and chemotherapy. There are currently several types of chemotherapy drugs available. There is also a brand new class of drugs called monoclonal antibodies that can destroy myeloma cells. These include daratumumab as well as elotuzumab. Combining these medications with other treatments enhances the results. Other treatments include immunotherapies, transplants and cellular vaccines.
Myeloma is a disease that can affect anyone of any age. However, certain aspects can increase the risk. People over age 45 and have an ancestor's history are at greater risk. People who have been in contact with radiation or chemicals also have a higher chance of developing. This includes those who have been exposed to Xrays, and those who were employed in industries that used asbestos, benzene, and herbicides such as Agent Orange.
Ronald Harris died of multiple myeloma in the year 2013. His estate sued csx transportation colon cancer Transportation, claiming that his railroad work was the cause of his cancer. The trial court held an evidentiary hearing to hear the testimony of three plaintiffs' experts in the field of science: Dr. Goldstein and Dr. Infante. The experts employed reliable methods to show that csx transportation pancreatic cancer diesel exhaust fumes resulted in Harris' myeloma. The evidence of the expert witness was based on human and animal studies and the chemical composition of diesel exhaust and closely related pyrogenic materials as well as studies on B-lymphocytes.
Prognosis
Multiple myeloma impacts the plasma cells. These cells are vital to the immune system, as they help the body fight diseases and infections. Plasma cells are constantly growing and enlarge the normal bone marrow in myeloma patients. This can cause other health problems, including low blood counts and bone damage.
Multiple myeloma is more prone to develop in those who have numerous risk factors. Age, family history and exposure to radiation as well as certain chemicals are all risk factors. A first-degree relative with multiple myeloma is twice as likely to develop it themselves. Myeloma is also more prevalent among blacks than white people.
Ronald Harris was a railroad trainman for csx transportation reactive airway disease csx transportation acute myeloid leukemia. He worked there for 29 years. He was exposed to diesel exhaust from locomotives on a daily basis. In the course of his work, Harris developed multiple myeloma, a type of cancer that attacks plasma cells in the bone marrow. Harris filed a lawsuit against csx transportation leukemia under the Federal Employers' Liability Act and the Locomotive Inspector Act. Harris tragically passed away during the time the case was still pending. His widow, Deborah Kay Harris, was appointed plaintiff.
The petitioner retained Dr. Peter Shields as an expert witness in the trial. During the two day hearing, both experts gave testimony about their backgrounds and the method they used to express their opinions. Both experts rely on the Bradford Hill methodology.
Peter worked for the Long Island Railroad Company for 29 years. During that time Peter was exposed to several hazardous chemicals. These substances and chemicals included creosote and diesel fumes.
Multiple myeloma is a cancer that affects plasma cells, which are responsible for producing antibodies to fight infections and diseases. These cancerous cells multiply within bones, forming cancerous tumors known as plasmacytomas.
Symptoms
The cancer affects plasma cells, which create antibodies that help the body fight germs and infections. The symptoms of multiple myeloma are bone pain in the back and ribs, brittle bones which break easily as well as fatigue, weakness loss of appetite, fatigue and kidney issues.
Often, myeloma does not cause symptoms until it is in its early stages. A doctor might not be aware of it until an annual blood or urine test for another condition has higher levels of protein than normal. This is known as myeloma smoldering. Myeloma can cause damage to organs, such as the kidneys, lungs, or nervous system in its later stages. This can result in vision and balance problems.
Your outlook is affected by the stage of your myeloma and other health conditions and also the age at which you were diagnosed. Your prognosis is also affected by how many plasma cells are producing tumors and creating complications as well as genetic factors that influence your risk of developing myeloma.
People who have a chromosomal anomaly known as deletion 17p or duplication 18q have a worse chance of surviving than people who don't have these disorders. If your kidneys do not perform as well, you'll have a less favorable prospect of survival. The amount of creatinine that you find in your blood is an excellent indicator of how your kidneys are working.
Diagnosis
Multiple myeloma is diagnosed after a person's blood or urine is tested for another illness and csx transportation pancreatic cancer more than the normal amount of protein is detected. Myeloma symptoms include bone pain, weakness of bones (including the back and ribs) and kidney issues, a fever without a known cause, bruising and difficult breathing.
The disease is more prevalent for people over the age of 60, and it is most often seen in males over 60. People with a first-degree relative who suffers from myeloma have 2 to 3 times greater risk of being diagnosed than other people. This includes siblings, parents, and children.
There are a variety of risk factors for myeloma. This includes a previous diagnosis of a single plasmacytoma of the bone or an extramedullary blood clot in soft tissue (such as the lung or throat). Myeloma is more frequent in people who have been exposed either to radiation or chemicals like asbestos, pesticides and benzene. Myeloma is also more prevalent for those who have a high monoclonal-gammopathy of unknown significance (MGUS).
The expert witnesses for the plaintiffs included two toxicologists and one epidemiologist. Toxicology refers to the science which studies the ways in which a chemical could be harmful and csx transportation pancreatic cancer the way exposure can cause a disease. Epidemiology studies the causes and effects, such as those caused by myeloma. This is accomplished by examining medical records and statistics.
Treatment
The treatment of myeloma focused on radiation and chemotherapy. There are currently several types of chemotherapy drugs available. There is also a brand new class of drugs called monoclonal antibodies that can destroy myeloma cells. These include daratumumab as well as elotuzumab. Combining these medications with other treatments enhances the results. Other treatments include immunotherapies, transplants and cellular vaccines.
Myeloma is a disease that can affect anyone of any age. However, certain aspects can increase the risk. People over age 45 and have an ancestor's history are at greater risk. People who have been in contact with radiation or chemicals also have a higher chance of developing. This includes those who have been exposed to Xrays, and those who were employed in industries that used asbestos, benzene, and herbicides such as Agent Orange.
Ronald Harris died of multiple myeloma in the year 2013. His estate sued csx transportation colon cancer Transportation, claiming that his railroad work was the cause of his cancer. The trial court held an evidentiary hearing to hear the testimony of three plaintiffs' experts in the field of science: Dr. Goldstein and Dr. Infante. The experts employed reliable methods to show that csx transportation pancreatic cancer diesel exhaust fumes resulted in Harris' myeloma. The evidence of the expert witness was based on human and animal studies and the chemical composition of diesel exhaust and closely related pyrogenic materials as well as studies on B-lymphocytes.
Prognosis
Multiple myeloma impacts the plasma cells. These cells are vital to the immune system, as they help the body fight diseases and infections. Plasma cells are constantly growing and enlarge the normal bone marrow in myeloma patients. This can cause other health problems, including low blood counts and bone damage.
Multiple myeloma is more prone to develop in those who have numerous risk factors. Age, family history and exposure to radiation as well as certain chemicals are all risk factors. A first-degree relative with multiple myeloma is twice as likely to develop it themselves. Myeloma is also more prevalent among blacks than white people.
Ronald Harris was a railroad trainman for csx transportation reactive airway disease csx transportation acute myeloid leukemia. He worked there for 29 years. He was exposed to diesel exhaust from locomotives on a daily basis. In the course of his work, Harris developed multiple myeloma, a type of cancer that attacks plasma cells in the bone marrow. Harris filed a lawsuit against csx transportation leukemia under the Federal Employers' Liability Act and the Locomotive Inspector Act. Harris tragically passed away during the time the case was still pending. His widow, Deborah Kay Harris, was appointed plaintiff.
The petitioner retained Dr. Peter Shields as an expert witness in the trial. During the two day hearing, both experts gave testimony about their backgrounds and the method they used to express their opinions. Both experts rely on the Bradford Hill methodology.
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