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작성자 Otto
댓글 0건 조회 22회 작성일 23-07-04 22:38

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Esophageal Cancer

Esophageal Cancer is a lethal cancer with one of the lowest rates of survival among cancers. The incidence rates vary based on the morphology of the tumor, and the anatomical site.

In Canada, EAC rates have doubled in the last 20 years. This could be due to the rising prevalence of obesity and gastroesophageal acid-reflux disease. However, ESCC rates declined during this period.

Background

The Esophageal canadian national railway colon cancer adenocarcinoma is the lowest survival rate of any malignancy found in the Western world. Observed rates of EAC have doubled in Canada, while those of squamous cell cancer of the esophagus (ESCC) have decreased, reflecting the increased prevalence of obesity and gastroesophageal reflux disease.

The prognosis for esophageal tumors is poor however, five-year relative survival has improved slightly over the past two decades. This could be due to the improved ability to detect and treat a tumor that is rapidly growing as well as the availability and efficacy of newer treatments such as chemotherapy and radiation therapy and improvements in the selection and treatment of patients.

The incidence rates and trends of EAC and ESCC vary based on tumour morphology and anatomical location. In Canada, the incidence rates of ESCC decreased while those of EAC doubled between 1986-2006. Estimated incidence rates suggest that the incidence rates of EAC will continue to rise and that those of ESCC will decline with a broad range of provinces experiencing both increases and decreases.

A variety of factors affect the prognosis for esophageal cancer as well as its grade (how much the cells appear like normal tissue) and whether it is located in the middle or upper esophagus. The degree of a cancer is determined by a pathologist using a microscope to look at the cells.

Methods

Adenocarcinoma and squamous cells carcinoma are the two main types of esophageal cancer. Canada's incidence rates are low when compared to the United States and other countries in northern Europe, Australia, New Zealand and Australia. However they have been rising in the past 20 years. The incidence trends differ based on the morphology of the tumour and its anatomic location as well as anatomic location. Rates of EAC doubling and those of ESCC decreasing from 1986 to 2006.

The five-year survival rate for esophageal carcinoma is rather low and decreases as you the time of diagnosis. About 15% of patients diagnosed are younger than 45 with men three to four times more likely to be afflicted.

A pathologist examines the cancerous cells with microscopes to determine the degree of the tumor. This is determined by the way the cancerous cells appear compared to normal ones. The higher the grade the more likely cancer will develop and spread. Your health care provider uses the grading system to determine the best treatment option for your specific situation. The grade of the tumor also aids your healthcare team to plan treatment follow-up. Patients with a tumour of a lower grade are screened less frequently than those with high grade tumours.

Results

The survival rate for esophageal carcinoma is among the lowest of all cancers. In Canada the five-year relative survival was 13% in 2006 as compared to 18 percent for the population as a whole (Table 1). The survival rates decrease with age and gender at diagnosis, but remain fairly stable in the upper and middle sections. On the other hand, Canadian National Railway Interstitial Lung Disease squamous cells cancer of the esophagus (ESCC) rates have declined since the beginning of the 1990s for men and women (Table 2). Alcohol and smoking increase the risk of cancer in ESCC. This accounts for 90% of cases. This decline is likely due to reduced smoking rates and the increased incidence of gastroesophageal reflux canadian national railway chronic obstructive pulmonary disease (45).

In Canada the prevalence of adenocarcinoma of the lower esophagus as well as squamous-cell carcinoma (ESCC) has contrasting trends. EAC rates have increased and ESCC rates have declined from 1986 to. The observed changes until 2026 were projected using the conventional cancer projecting model, Nordpred (23) and were further categorized based on tumor shape and size, as well as anatomical location. Projections showed an increase of 40 to 50 percent in the incidence of esophageal carcinoma and decreases of 30 to 50 percent for squamous cell cancers of the upper, middle and lower esophagus segments. This increase in EAC is likely due increased rates of obesity and gastroesophageal disease, however, the decreases in ESCC may result from a reduction in smoking.

Conclusions

While the five-year survival rate for esophageal cancer remains very low, it has increased somewhat since the beginning of the 1990s, mainly in response to more precise staging using ultrasound of the esophageal area and preresection stage through laparoscopy or thoracoscopy, which includes biopsy of the celiac-axis and less curvature. The increase is mainly restricted to those between 45- 70 years old. In this age group the prevalence rate of EAC doubled. In contrast, canadian national railway Blood cancer ESCC has decreased in both genders.

Smoking rates could have decreased and this could explain the decrease in ESCC. Given the relatively low survival rates for esophageal cancer, efforts to reduce risk factors and develop more efficient treatment strategies are necessary.

Canadian national railway all stages 0 and 1 esophageal tumors, as well as the majority of stage 3 cancers which have not spread to the spinal cord, aorta and trachea are potentially resectable. The majority of patients with advanced cancers that have advanced to these vital organs or lymph nodes that are distant are not candidates for canadian national railway all surgery. These patients should receive chemotherapy, either with or without radiation therapy. Stage 4 esophageal cancers are not suitable for treatment with surgery, however they may be treated with medications that hinder cell growth or stop cancer cells from spreading.

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